NEW YORK—The New York Genome Center (NYGC) has signed a 20-year, 170,000-sq.-ft. lease to occupy space at Edward J. Minskoff Equities Inc.’s 101 Avenue of the Americas. The space, which will serve as NYGC’s headquarters, spans seven floors of the newly renovated, LEED Silver-certified building.

Construction of the space began this month and the $47 million build-out is expected to be completed by mid-2013. The space will include sequencing, bioinformatics, and research labs; an innovation center; and sophisticated computing infrastructure.

The facility will also include a ground-floor auditorium and café, training facilities and administrative offices. Initially housing 100 employees, the center is expected to grow to accommodate more than 500 employees over the first five years of operations.

NYGC began offering sequencing, bioinformatics and data storage services in February 2012.

Founded in 2010, NYGC is an independent nonprofit that works to bring together leaders in science and medicine. Founding members include Cold Spring Harbor Laboratory; Columbia University; Cornell University/Weill Cornell Medical College; The Jackson Laboratory; Memorial Sloan-Kettering Cancer Center; Mount Sinai Medical Center; New York-Presbyterian Hospital; New York University/NYU School of Medicine; North Shore-LIJ Health System; The Rockefeller University; and Stony Brook University. The Hospital for Special Surgery is an Associate Founding Member.